Insertion sequence elements-mediated structural variations in bacterial genomes
نویسندگان
چکیده
منابع مشابه
Structural variations in plant genomes
Differences between plant genomes range from single nucleotide polymorphisms to large-scale duplications, deletions and rearrangements. The large polymorphisms are termed structural variants (SVs). SVs have received significant attention in human genetics and were found to be responsible for various chronic diseases. However, little effort has been directed towards understanding the role of SVs...
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Genomic structural variations (SVs) are pervasive in many types of cancers. Characterizing their underlying mechanisms and potential molecular consequences is crucial for understanding the basic biology of tumorigenesis. Here, we engineered a local assembly-based algorithm (laSV) that detects SVs with high accuracy from paired-end high-throughput genomic sequencing data and pinpoints their brea...
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ژورنال
عنوان ژورنال: Mobile DNA
سال: 2018
ISSN: 1759-8753
DOI: 10.1186/s13100-018-0134-3